New bone defect filler<br> designated for <br>regenerative medicine

New bone defect filler
designated for
regenerative medicine

Patients

About the product

FlexiOss® Dent is a modern implantable biomaterial of third generation:    Biphasic (hydroxyapatitepolymeric), bioactive, supporting the regeneration of bone tissue and a potential drug carrier.           

The combination of two main compounds of composite was performed by polymer gelling into the structure of irreversible, collagen-like triple helix – the conformation which does not evoke the appearance of local inflammation processes and enables the entrapment of HAP granulate.

After implantation undergoes an integration with patient’s bone tissue in beneficial manner and is slowly remodelled and replaced with natural bone tissue. This eliminates the necessity of reoperation in order to remove the implanted biomaterial. Thus, the patient’s stress and pain is limited to the minimum.

Available in 3 sizes: 1 cm, 3 cm and 5 cm.

Flexible after soaking: plastic and bendable.

Properties

flexible after soaking
(plastic and bendable)
bio-compatible with
natural bone tissue
mechanical parameters similar
to those of cancellous bone
actively supports bones
reconstruction process
absorbs blood
and medicine solutions
positively influences the bone tissue regeneration process
ionic reactive / bioactive
non-toxic material
can be used for defects of
up to 7 cm in length
non-animal material (lowering risk
of pathogens transmission and appearance
of allergic reactions)
easy to carry and store

Surgical handiness

Surgical handiness, which allows to fit it during the operation to the shape of individual bone defects by cutting or bending.

Can be milled

In a dry state, FlexiOss®Dent can be milled which enables the personalization of the composite implant.

Faster ossification

High specific surface area (due to the high microporosity of granules), high ionic reactivity (adsorption of calcium and phosphate ions from surroundings liquid which allows to increase the rate of mineralization within the implantation site and increase the rate of new bone tissue formation).

Minimizes the risk of viruses and prions contamination

Application of carbohydrate polymer to produce FlexiOss® composite minimizes the risk of viruses and prions contamination. Curdlan undegoes gelling, forming the structure of irreversible, collagen-like triple helix – the conformation which is neutral for macrophages and does not evoke the appearance of local inflammation.

High soaking capacity

FlexiOss®Dent exhibit high soaking capacity. This simplify the nutrient supply to the biomaterial within the implantation site and removal of metabolic degradation products, thus increasing the rate of bone tissue regeneration. Before the implantation, it can be soaked in solution of antibacterial drugs, thus minimizing the risk of perioperative infections and implant rejection. Due to its properties, it can be also soaked in, for example, platelet rich plasma (PRP) and solution of growth factors (commercial or isolated from patient’s blood). Thus, the biomaterial may resemble (in its properties) very expensive bone-substitutes containing BMP-2-type growth factors.

Can be easily stored and transported

Can be easily stored and transported.

Treatment

  • Oława

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  • Lublin

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  • Warszawa

    Góra Kalwaria

    Siedlce

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  • Gdańsk

  • Częstochowa

    Dąbrowa Górnicza

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  • Chodzież

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Contact

Medical Inventi S.A.
ul. Nałęczowska 14
20-701 Lublin
woj. lubelskie, Polska
biuro@medicalinventi.pl
NIP: 946-262-83-41
REGON: 060772285
KRS: 0000544357

Sales and Marketing
Aleksandra Machowska
aleksandra.machowska@medicalinventi.pl
tel. +48 881 750 883

Quality Department
Katarzyna Siwiec
katarzyna.siwiec@medicalinventi.pl
tel. +48 881 611 883
Olga Kruk
olga.kruk@medicalinventi.pl
tel. +48 881 550 883

Administration, EU projects
Olga Orzechowska
olga.orzechowska@medicalinventi.pl
tel. +48 667 330 883

Bank account mBank
97 1140 1094 0000 2789 8000 1001

Sąd Rejonowy Lublin-Wschód w Lublinie z siedzibą w Świdniku
VI Wydział Gospodarczy Krajowego Rejestru Sądowego
Kapitał zakładowy: 340,382.20 zł

www.medicalinventi.pl